Core Material

• The basics of SPE – A Gentle Introduction
• Understanding the behaviour of bonded phase silica’s
• Reverse Phase (Non Polar) SPE method development and optimisation.
• Normal Phase (Polar) SPE method development and optimisation.
• Ion Exchange Principles Practice and Techniques.Method Development and optimisation.

Applications for Bioanalysis

• Handling Biological samples specific sorbents for general screening.
• High Throughput applications using 96 well plates and linking up with LC/MS
• Extracting Drugs and Metabolites from Solid Samples.
• Clean up strategies for protein digests prior to MALDI TOF MS analysis.
• Automation strategies and applications of New and emerging SPE Technologies including membrane based phases.
• Summary of key issues in methods development